I hit this error while trying to register a plugin assembly in CRM 2011.
Error message is very generic :)
Generic SQL error.
System.Data.SqlClient.SqlException: Microsoft Dynamics CRM has experienced an error. Reference number for administrators or supportThe root cause of this error is database log file is running out of disk space, is full!
Just do a simple housekeeping will solve the issue.
Hope this help. Happy CRM'ing